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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Apoptosis. 2014 Nov;19(11):1581–1593. doi: 10.1007/s10495-014-1022-z

Fig. 4.

Fig. 4

Apoptosis and proliferation for combined markers Apaf1, Bcl2 and p53. Apoptosis (M30, IHC) and proliferation (Ki-67, IHC) were combined and compared to the methylation percentages of the markers Apaf1, Bcl2 and p53. Patients with data for all markers available (n = 78) were classified into high or low apoptosis or proliferation groups based on the median number or percentage of positive tumor cells, respectively. For all combined marker groups, the number of patients in each of the combined apoptosis-proliferation categories was determined (a). Kaplan–Meier curves were made to visualize survival differences for the combined apoptosis-proliferation categories (b)