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. 2015 Mar 3;49(1):80–85. doi: 10.2478/raon-2014-0021

TABLE 3.

Adverse events

Without AE n (%) G1
n (%)
G2
n (%)
G3
n (%)
G4
n (%)
Hematopoietic toxicity
leukopenia 16 (84) 2 (10.5) 1 (5.3) 0 0
neutropenia 17 (89.5) 1 (5.3) 1 (5.3) 0 0
lymphopenia 13 (68.4) 6 (31.6) 0 0 0
thrombocytopenia 17 (89.5) 2 (10.5) 0 0 0
anemia 16 (84.2) 3 (15.8) 0 0 0
febrile neutropenia 0 / / / 0
Non-hematopoietic toxicity
arterial hypertension 16 (84.2) 2 (10.5) 1 (5.3) 0 0
proteinuria 12 (63.2) 3 (15.8) 3 (15.8) 1 (5.2) /
sepsis 0 / / / 0
diarrhea 18 (94.7) 1 (5.3) 0 0 0
vomiting 17 (89.5) 1 (5.3) 1 (5.3) 0 0
muscle pain 18 (84.7) 1 (5.3) 0 / /
intracranial hemorrhage 0 0 0 0 0
tromboembolic event 0 0 0 0 0

0 = no adverse side effects; / = adverse events of this grade doesn’t exist