Table 1.
Physiological characteristics of GIPR dn transgenic pigs one week prior to the start of liraglutide/placebo treatment
| Parameter | Control group | Treatment group | P |
|---|---|---|---|
| (Placebo) | (Liraglutide) | ||
| n = 9 | n = 9 | ||
| 4 m, 5 f | 4 m, 5 f | ||
| Age [days] | 60 ± 0.14 | 60 ± 0.14 | 1.00 |
| Body weight [kg] | 15 ± 1.00 | 16 ± 0.73 | 0.41 |
| MMGTT | |||
| AUC glucose | 17839 ± 682 | 18375 ± 881 | 0.80 |
| AUC insulin | 2956 ± 187 | 3296 ± 261 | 0.30 |
| IVGTT | |||
| AUC glucose | 13015 ± 592 | 12821 ± 458 | 0.86 |
| AUC insulin | 719 ± 69 | 862 ± 75 | 0.08 |
m = male, f = female, MMGTT = mixed meal glucose tolerance test, IVGTT = intravenous glucose tolerance test, AUC = area under the curve. Data are means ± SEM.