Table 2.

Potential neuroprotective agents in glaucoma patients

Mechanism	Agents	Administration	Clinical effects in glaucoma patients	References
Supplementation of neurotrophic factors	NGF	Topical	Improvements in visual field, optic nerve function, and contrast sensitivity	22
Blockage of excitotoxicity	Nilvadipine	Oral	Slowing of visual field defect progression and maintenance of optic disc rim	39
	Betaxolol	Topical	Improvement in visual field mean sensitivity index	41
Inhibition of apoptosis	Brimonidine	Topical	Slowing of visual field defect progression	84
Suppression of oxidative stress	Ginkgo biloba	Oral	Slowing of visual field defect progression	58

Abbreviation: NGF, nerve-growth factor.