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. Author manuscript; available in PMC: 2015 Mar 17.
Published in final edited form as: Curr Protoc Pharmacol. 2013 Oct 8;62:Unit–14.27.. doi: 10.1002/0471141755.ph1427s62

Figure 14.27.1.

Figure 14.27.1

Implantation of NSCLC cells to generate a mouse orthotopic lung tumor model. (A) A 3-mm incision is made in the area of the left lateral thorax. Soft tissue is removed to expose the thoracic ribs and intercostal space to allow visualization of the left lobe of the lung. (B) NSCLC cells are injected by quickly advancing the needle to a depth of approximate 5 mm into the left lobe of the lung between the 6th and 7th rib and injecting the cell suspension. (C) The incision site is closed with 2 or 3 sterile wound clips.