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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Ann Surg. 2014 May;259(5):999–1006. doi: 10.1097/SLA.0b013e31829a4352

Figure 1.

Figure 1

In vivo endotoxin-induced responses in humans. Subjects (n=5 per group) were challenged with saline (placebo group) or endotoxin at 1-, 0.5- or 0.1-ng/kg. Subjects were assigned a unique color and symbol code that can be followed throughout Figures 1-4. Endotoxin-induced systemic changes in core body temperature, hear rate (HR), and cytokine (IL-6 and TNF) responses were monitored at the indicated time post-infusion. The panels in the left hand column represent mean responses. All other panels show dose- and time-dependent responses per subject.