Table 1. Differentially expressed genes in vertex vs frontal scalp.
The Affymetrix probe IDs, Gene Symbols, Gene Description and fold-changes of the differentially expressed are shown. The down regulated genes include those that encode stress response proteins (pink highlight), keratin-associated proteins (yellow highlight) and non-coding RNA transcripts (green highlight). Five genes including non-coding RNAs were up regulated in the vertex compared to the frontal scalp.
| Probe id | Gene symbol Down regulated |
Fold change avg | Gene description |
|---|---|---|---|
| 8115831 | ATF3 | −1.954440184 | “Homo sapiens activating transcription factor 3 (ATF3), transcript variant 4, mRNA. ” |
| 7975779 | CYR61 | −1.998588958 | “Homo sapiens cysteine-rich, angiogenic inducer, 61 (CYR61), mRNA. ” |
| 8029693 | DUSP1 | −2.431645062 | “Homo sapiens dual specificity phosphatase 1 (DUSP1), mRNA. ” |
| 7902687 | EGR1 | −1.895999069 | “Homo sapiens early growth response 1 (EGR1), mRNA. ” |
| 7946033 | EFCAB4B | −1.906824031 | “Homo sapiens EF-hand calcium binding domain 4B (EFCAB4B), transcript variant 1, mRNA. ” |
| 8108627 | FOSB | −2.327675169 | “Homo sapiens FBJ murine osteosarcoma viral oncogene homolog B (FOSB), transcript variant 1, mRNA. ” |
| 8005547 | HBB | −1.862261909 | “Homo sapiens hemoglobin, beta (HBB), mRNA. ” |
| 7984259 | KRTAP19-1 | −1.854118595 | “Homo sapiens keratin associated protein 19-1 (KRTAP19-1), mRNA. ” |
| 7981730 | KRTAP19-3 | −2.205875048 | “Homo sapiens keratin associated protein 19-3 (KRTAP19-3), mRNA. ” |
| 7967028 | KRTAP8-1 | −2.076531532 | “Homo sapiens keratin associated protein 8-1 (KRTAP8-1), mRNA. ” |
| 8005553 | MS4A1 | −2.24590692 | “Homo sapiens membrane-spanning 4-domains, subfamily A, member 1 (MS4A1), transcript variant 1, mRNA. ” |
| 7948894 | IGLJ3 | −2.121862356 | “Homo sapiens mRNA for scFv collagenase IV antibody, complete cds. ” |
| 8013329 | PSG3 | −1.783784365 | “Homo sapiens pregnancy specific beta-1-glycoprotein 3 (PSG3), mRNA. ” |
| 7942594 | RNU2-1 | −1.991355015 | “Homo sapiens RNA, U2 small nuclear 1 (RNU2-1), non-coding RNA. ” |
| 7940287 | RNU4-2 | −2.280746608 | “Homo sapiens RNA, U4 small nuclear 2 (RNU4-2), non-coding RNA. ” |
| 7920873 | RNU5B-1 | −1.843214714 | “Homo sapiens RNA, U5B small nuclear 1 (RNU5B-1), non-coding RNA. ” |
| 7909610 | RNU5E | −1.902622286 | “Homo sapiens RNA, U5E small nuclear (RNU5E), non-coding RNA. ” |
| 7960365 | SCARNA5 | −2.037973907 | “Homo sapiens small Cajal body-specific RNA 5 (SCARNA5), non-coding RNA. ” |
| 7897801 | SNORD15B | −1.843219815 | “Homo sapiens small nucleolar RNA, C/D box 15B (SNORD15B), non-coding RNA. ” |
| 8013325 | SNORD3A | −1.902175302 | “Homo sapiens small nucleolar RNA, C/D box 3A (SNORD3A), non-coding RNA. ” |
| 8133688 | SNORD3A | −1.902175302 | “Homo sapiens small nucleolar RNA, C/D box 3A (SNORD3A), non-coding RNA. ” |
| 8014755 | SNORD3A | −1.902175302 | “Homo sapiens small nucleolar RNA, C/D box 3A (SNORD3A), non-coding RNA. ” |
| 8028652 | SNORD3A | −1.902175302 | “Homo sapiens small nucleolar RNA, C/D box 3A (SNORD3A), non-coding RNA. ” |
| 8037231 | SNORD3A | −1.902175302 | “Homo sapiens small nucleolar RNA, C/D box 3A (SNORD3A), non-coding RNA. ” |
| 8049297 | SNORD82 | −1.856869421 | “Homo sapiens small nucleolar RNA, C/D box 82 (SNORD82), non-coding RNA. ” |
| 8059712 | SNORA14A | −1.7275943 | “Homo sapiens small nucleolar RNA, H/ACA box 14A (SNORA14A), non-coding RNA. ” |
| 8062490 | SNORA21 | −1.825872603 | “Homo sapiens small nucleolar RNA, H/ACA box 21 (SNORA21), non-coding RNA. ” |
| 8069822 | SNORA42 | −2.127392366 | “Homo sapiens small nucleolar RNA, H/ACA box 42 (SNORA42), non-coding RNA. ” |
| 8069831 | SNORA60 | −1.890606752 | “Homo sapiens small nucleolar RNA, H/ACA box 60 (SNORA6O), non-coding RNA. ” |
| 8069863 | SNORA74A | −1.867939307 | “Homo sapiens small nucleolar RNA, H/ACA box 74A (SNORA74A), non-coding RNA. ” |
| 8108370 | VTRNA1-1 | −2.631698263 | “Homo sapiens vault RNA 1-1 (VTRNA1-1), non-coding RNA. ” |
| 8108420 | FOS | −4.412605768 | “Homo sapiens v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS), mRNA. ” |
| 8013323 | ZFP36 | −1.746605695 | “Homo sapiens zinc finger protein 36, C3H type, homolog (mouse) (ZFP36), mRNA. ” |
| Up regulated | |||
| 8059852 | ANKRD20B | 1.832236142 | “Homo sapiens ankyrin repeat domain 20B (ANKRD20B), non-coding RNA. ” |
| 8020349 | CD209 | 1.620675753 | “Homo sapiens CD209 molecule (CD209), transcript variant 2, transcribed RNA. ” |
| 8169504 | MSL3L2 | 2.23003259 | “Homo sapiens male-specific lethal 3-like 2 (Drosophila) (MSL3L2), non-coding RNA. ” |
| 8095504 | MUC7 | 1.730630286 | “Homo sapiens mucin 7, secreted (MUC7), transcript variant 1, mRNA. ” |
| 8025301 | SLC6A14 | 1.780898386 | “Homo sapiens solute carrier family 6 (amino acid transporter), member 14 (SLC6A14), mRNA. ” |