Table 1.

Distribution of total VSCI values according to IFNg/IL-10 constellations in the positive-sensitization group

Group	Description of group	Number of patients	VSCI values	Validation quotient
1	IFNg positive/IL-10 negative	61	389	6.38
2	IL-10 positive/IFNg negative	100	542	5.42
3	IFNg positive/IL-10 positive	21	119	5.67

Notes: The total VSCI values before extraction of RFT are reported. Group 1 represents patients with unbalanced TH1-dominant sensitization; group 2 corresponds to patients with latent (balanced) sensitization; and group 3 includes patients who have partially balanced TH1-dominant sensitization. A positive sensitization consists of patients sensitized by exposure to Merc/Thio and the degree of immunological sensitization is defined by the level of IFNg and IL-10, where IFNg is >0.3 IU/mL and/or IL-10 is >10 IU/mL.

Abbreviations: Merc/Thio, mercaptan and thioether; RFT, root-filled teeth; VSCI, volatile sulfur compound indicator; IFNg, interferon gamma.