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. Author manuscript; available in PMC: 2016 Apr 13.
Published in final edited form as: Eur J Med Chem. 2014 Sep 16;94:480–488. doi: 10.1016/j.ejmech.2014.09.047

Figure 1.

Figure 1

Analysis of a diseased signaling network gives rise to specific protein complexes of interest, after which that complex is analyzed to identify minimal units of structure relevant for mimicry. Finally, a specific inhibitor molecule is designed based on that sub-structure.