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. Author manuscript; available in PMC: 2016 Apr 13.
Published in final edited form as: Eur J Med Chem. 2014 Sep 16;94:480–488. doi: 10.1016/j.ejmech.2014.09.047

Table 2.

Sos segments that may serve as plausible starting points for inhibitor design.1

Residue Range Interface With Secondary Structure? Total ΔΔG
825-829 R Yes 4.85
880-884 R No 2.58
908-912 R No 4.48
929-944 R Yes 14.1
1007-1010 R Yes 1.88
683-695 Q Yes 10.47
729-739 Q Yes 5.79
750-755 Q No 3.05
973-974 Q Yes 3.02