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Ras possesses one (β-strand sequence and one lone residue that may serve as plausible starting points for inhibitor design, while Raf possesses two low-affinity sequences.
| Residue Range | Interface With | Secondary Structure? | Total ΔΔG |
|---|---|---|---|
| 36A-40A | B | Yes | 5.68 |
| 54A | B | No | 3.68 |
| 72B-74B | A | Yes | 2.25 |
| 81B-86B | A | Yes | 5.02 |
