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. 2015 Mar 17;10(3):e0119769. doi: 10.1371/journal.pone.0119769

Fig 7. Topical treatment with US-activated OLNDs effectively enhances tcpO 2 in vivo.

Fig 7

The shaved abdomens of eight anesthetized mice were topically treated with OLND gel formulation and sonicated (f = 1 MHz; P = 5 W; t = 30 sec). Before and after treatment, tcpO 2 was monitored through transcutaneous oxymetry. Panel A. Short-term time-course (0–15 min) tcpO 2 monitoring of three mice before and after treatment with OLND gel formulation. Data are shown as means ± SD. Results were also analyzed for statistical significance by Student’s t test. Versus untreated mice: p < 0.01. B. Long-term end-point (1 h) tcpO 2 measurement of five mice (m1-m5) before and after treatment with OLND gel formulation. Data are shown individually per each mouse.