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. 2015 Mar 17;10(3):e0119486. doi: 10.1371/journal.pone.0119486

Fig 9. Evaluation of the immune response to the cationic polymers.

Fig 9

Humoral immune response evaluation by ELISA on day 36 of the experiment. The levels of IgG specific toward different UFH inhibitors in individual mice presented as values of absorbance in ELISA test. The inserted graph shows mean ELISA signals corresponding to the levels of anti-protamine-, anti-Dex40-GTMAC2- or Dex40-GTMAC3-IgG present in sera of mice immunized with matching UFH-antidotes (gray bars) compared to the signals from sera of control mice treated with UFH alone (black bars). All sera applied in 1:100 dilution, b-P<0.01, Mann-Whitney test. Results are shown as mean ± SD, n = 5.