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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Int J Behav Med. 2015 Jun;22(3):283–291. doi: 10.1007/s12529-014-9417-3

Table 1.

RE-AIM Model dimensions and potential role of system science methods for each

MODEL
DIMENSIONS
SYSTEMS SCIENCE METHODS
System Dynamics Agent-Based Modeling Social Network Analysis
Reach: What proportion and how representative are participants of the target population? Explicate determinants of less-than-optimal reach and potential solutions. Critically synthesize existing knowledge and data to determine model specifications and settings; Articulate multi-level key influencing factors, the theoretical mechanistic relationships and establish parameters. Identify peripheral and isolated members of the target population who may be difficult to reach.
Effectiveness: What is the success rate if implemented according to intervention protocol? Study dynamic determinants of the impact of intervention, intended and otherwise; may quantify if value sufficient. Simulate the impact of the intervention on agent behavior. Test proximal and distal relational outcomes of programs (e.g., increased communication; increased social capital).
Adoption: What proportion of people/settings/practices will adopt/participate in the intervention? Bring together potential adopters to study challenges to adoption Explore spread of behaviors and reach of intervention by varying influencing factors. Examine the role the relationships play in access to information about and decisions to adopt new interventions; Understand how individuals’ positions in the network influence their propensity to adopt the intervention; Identify influential community members who can assist in encouraging adoption.
Implementation: To what extent is the intervention implemented as intended in the real-world? Diagram potential short term threats to successful implementation and indirect consequences of implementation that might undermine impact Simulate “real-world” setting and explore impact of multiple intervention configurations (e.g. community wide verses spatially focused). Understand how individuals’ positions in the network influence their frequency of implementation; Identify influential community members who can assist in implementation.
Maintenance: To what extent is the program sustained over time? What happens to the program over time? Diagram potential threats to longer-term maintenance, and how each might be avoided/addressed Run multiple iterations of the models to explore what happens to the spread and dynamics of targeted behaviors. Identify areas of the network to strengthen for D&I efforts and create recommendations; Identify influential community members who can sustain the program over time