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Possible dose-efficacy relationships for I = 4 dose levels.
| Shape of relationship | Location of node | Possible Dose-efficacy relationship |
|---|---|---|
|
| ||
| Unimodal or plateau | d1 | πE(d4) ≤ πE(d3) ≤ πE(d2) ≤ πE(d1) |
| Unimodal or plateau | d2 | πE(d1) ≤ πE(d3) ≤ πE(d4) ≤ πE(d2) |
| Unimodal or plateau | d3 | πE(d1) ≤ πE(d2) ≤ πE(d4) ≤ πE(d3) |
| Unimodal | d4 | πE(d1) ≤ πE(d2) ≤ πE(d3) ≤ πE(d4) |
