Table 2.

Operating characteristics of the proposed design and Hoering et al. (2013). Overall probability of selecting a best or good dose level as the OBD after 1000 simulation runs with a maximum sample size of N = 64 patients.

Efficacy Scenario	Toxicity Scenario	Best Dose Level	Good Dose Level	Probability of Picking Best Dose with Our Proposed Design	Probability of Picking Good Dose with Our Proposed Design	Probability of Picking Best Dose with Hoering et al. Design	Probability of Picking Good Dose with Hoering et al. Design
R1	T1	4	4	0.61	0.61	0.21	0.21
R1	T2	4	4	0.54	0.54	0.20	0.20
R1	T3	4	4	0.39	0.39	0.31	0.31
R1	T4	6	4–6	0.57	0.92	0.63	0.89
R2	T1	4	3, 4	0.70	0.94	0.30	0.68
R2	T2	4	3, 4	0.61	0.85	0.30	0.65
R2	T3	4	3, 4	0.59	0.67	0.42	0.71
R2	T4	4–6	3–6	0.94	0.99	0.91	0.94
R3	T1	1–4	1–4	0.99	0.99	0.93	0.93
R3	T2	1–4	1–4	0.98	0.98	0.90	0.90
R3	T3	1–4	1–4	0.95	0.95	0.84	0.85
R3	T4	1–6	1–6	1.00	1.00	0.97	0.97