A: BMP Receptor 2. BMPR2 expression was reduced in ESC exposed to LCM, compared to control non-LCM exposed ESC (0.59 fold, p<0.05). Pre-incubation of LCM with TGF-β neutralizing antibody, prior to ESC exposure, prevented repression of BMPR2 expression.
B: BMP Receptor 1B. BMPR1B expression was reduced in ESC exposed to LCM, compared to control non-LCM exposed ESC (0.61 fold, p<0.05). Pre-incubation of LCM with TGF-β neutralizing antibody, prior to ESC exposure, prevented repression of BMPR1B expression.
C: BMP Receptor 1A. BMPR1A expression was not significantly changed in LCM exposed ESC, compared to control non-LCM exposed ESC.
* denotes statistical significance with p<0.05