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Serial sections of human involuting breast tissue demonstrate immune cells in very close proximity to breast epithelium. Representative immunohistochemical staining (brown) for the epithelial cell marker cytokeratin 18 (CK18), the general leukocyte marker CD45, and the macrophage marker CD68 are shown. CD45 and CD68 positive cells within the breast epithelium are indicated with arrows and arrowheads, respectively. Modified with permission from O’Brien et al. [39]
