Table 3.
Independent Predictors of Shock on Multivariate Cox Proportional Hazard Model
| Unmatched (N=1509) | Propensity Matched (N=574) | |||
|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | |
| ACEi/ARB *GFR | <.001 | 0.046 | ||
| ACEi/ARB (+), GFR (>60 ml/min/1.73m2) | 1.0 (Ref) | --- | 1.0 (Ref) | --- |
| ACEi/ARB (+), GFR (30–60 ml/min/1.73m2) | 1.28 (0.96–1.69) | 0.09 | 1.17 (0.65–2.11) | 0.61 |
| ACEi/ARB (+), GFR (<30 ml/min/1.73m2) | 2.35 (1.32–4.19) | 0.004 | 1.81 (0.69–4.78) | 0.23 |
| ACEi/ARB (−), GFR (>60 ml/min/1.73m2) | 1.45 (1.05–2.01) | 0.02 | 1.68 (1.08–2.62) | 0.02 |
| ACEi/ARB (−), GFR (30–60 ml/min/1.73m2) | 2.05 (1.32–3.16) | 0.001 | 2.15 (1.26–3.66) | 0.005 |
| ACEi/ARB (−), GFR (<30 ml/min/1.73m2) | 2.41 (1.18–4.95) | 0.02 | 2.34 (0.96–5.66) | 0.06 |
| Age (years) | 0.98 (0.97–0.99) | <.001 | 0.98 (0.97–0.99) | 0.04 |
| Systolic Blood Pressure (mm Hg) | 0.99 (0.99–1.00) | 0.03 | --- | --- |
| Ejection Fraction (%) | 0.98 (0.96–0.99) | 0.04 | 0.97 (0.94–0.99) | 0.03 |
| QRS (ms) | 1.004(1.001–1.007) | 0.02 | 1.005 (1.00–1.01) | 0.05 |
| Women | 0.70 (0.51–0.97) | 0.03 | --- | --- |
| Race (African American) | 1.65 (1.23–2.23) | 0.001 | --- | --- |
| Ischemic etiology | 1.39 (1.05–1.84) | 0.02 | 2.16 (1.29–3.62) | 0.003 |
| Digoxin | 1.24 (0.97–1.55) | 0.054 | --- | --- |
| Anti-arrhythmics | 1.60 (1.25–2.04) | <.001 | 1.44 (0.98–2.10) | 0.06 |