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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Mucosal Immunol. 2014 Sep 17;8(3):516–532. doi: 10.1038/mi.2014.85

Figure 5.

Figure 5

Chronic allergic asthma presents with a less severe clinical phenotype in IgER-TG animals. (a) Airway hyper-responsiveness (airway resistance, Rn) without and with methacholine challenge. (b) Infiltration of mast cell/basophils in lung tissue quantified by using mRNA levels of the cell-type specific marker FcεRI β-chain. Symbols are representative of individual mice ≥ 2 independent experiments. (c) mRNA profiling of lung tissue after induction of allergic asthma. (d) Counts of neutrophils and eosinophils in the bronchoalveolar lavage fluid of sensitized (+) WT and IgER-TG mice. Symbols represent individual mice of 2 independent experiments. Due to the high biological variation of the tissue response no statistical significance was reached.