Table 1.
Patients’ demographic data and clinical characteristics
| Hospital survivors | Hospital non-survivors | P -value | |
|---|---|---|---|
| (n = 53) | (n = 13) | ||
| Age, years | 60 (45 to 76.5) | 59 (45 to 84) | 0.640 |
| Gender, M/F, number | 29/24 | 9/4 | 0.532 |
| BMI, kg/m2 | 25.9 ± 4.0 | 25.2 ± 3.7 | 0.597 |
| Body weight, kg | 67.6 ± 12.1 | 69.2 ± 11.8 | 0.671 |
| Etiology, alcohol/biliary/ERCP/others | 19/31/0/3 | 6/6/1/0 | 0.145 |
| Leukocytes, ×109/l | 11.8 ± 5.7 | 14.6 ± 0.9 | 0.301 |
| Hemoglobin, g/dl | 10.4 ± 2.1 | 10.3 ± 2.6 | 0.893 |
| Platelets, ×109/l | 157.5 (88.3 to 241) | 62 (25 to 216) | 0.043 |
| BUN, mg/dl | 17.5 (10.8 to 26.5) | 44 (14.5 to 91.5) | 0.009 |
| Serum creatinine, mg/dl | 0.9 (0.7 to 1.9) | 3.1 (1.8 to 5.4) | 0.003 |
| Bilirubin, mg/dl | 1.5 (0.9 to 3) | 8 (2.7 to 22. 5) | <0.001 |
| INR | 1.2 (1.1 to 1.4) | 1.5 (1.2 to 1.8) | 0.007 |
| Ranson score | 5 (4 to 6) | 6 (6 to 8.5) | 0.001 |
| APACHE II score | 15 (11 to 20.8) | 28 (16.5 to 34.8) | 0.002 |
| SOFA score | 5 (3 to 8) | 13 (6.5 to 15.8) | 0.001 |
| Modified Marshall score | 3 (2 to 5.5) | 9.5 (7 to 10.8) | <0.001 |
| Organ failure | 42 (79.2%) | 13 (100%) | 0.104 |
| Number of organ failures | 1 (1 to 2) | 3 (2 to 3) | <0.001 |
| Respiratory failure | 38 (71.7%) | 12 (92.3%) | 0.162 |
| Renal failure | 21 (39.6%) | 11 (84.6%) | 0.005 |
| Cardiovascular failure | 13 (24.5%) | 11 (84.6%) | <0.001 |
| Infected necrosis, n | 10 (18.9%) | 8 (61.5%) | 0.002 |
| Persistent organ failure, n | 22 (41.5%) | 13 (100%) | <0.001 |
| Cholesterol, mg/dl | 122 (92 to 152) | 98 (81 to 139) | 0.256 |
| Triglyceride, mg/dl | 140 (107 to 239) | 180 (102 to 362) | 0.723 |
| HDL, mg/dl | 17 (11 to 31) | 6 (4 to 13) | <0.001 |
| LDL, mg/dl | 61 (40 to 79) | 43 (30 to 91) | 0.297 |
| APO A-I, mg/dl | 67 (50 to 83) | 40 (23 to 46) | <0.001 |
| IL-6, pg/ml | 73 (39.7 to 177.8) | 388 (125 to 831.5) | 0.015 |
| TNF-α, pg/ml | 6.2 (2.9 to 13.5) | 25 (20 to 42) | 0.011 |
| CRP, mg/l | 182.6 ± 115.6 | 151.6 ± 77.4 | 0.382 |
Results are presented as mean ± SD, or median (IQR) unless otherwise stated. M, male; F, female; BMI, body mass index; ERCP, endoscopic retrograde cholangiopancreagraphy; BUN, blood urea nitrogen; INR, international normalized ratio; APACHE, acute physiology, age, and chronic health evaluation; SOFA, sequential organ failure assessment; HDL, high-density lipoprotein; LDL, low-density lipoprotein; APO, A-I apolipoprotein A-I; CRP, C-reactive protein.