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. 2015 Mar 18;35(11):4706–4718. doi: 10.1523/JNEUROSCI.4276-14.2015

Figure 5.

Figure 5.

Effects of rapamycin treatment on S6K1 and S6 phosphorylation in the cerebellum of WT and AS mice. A, C, Representative images of Western blot processed for p-S6K1 (389), S6K1, p-S6 (235/236), p-S6 (240/244), and S6 in P2 (A) and S2 (C) fractions. B, D, Quantitative analysis of Western blots shown in A and C (means ± SEMs from 3–5 mice; *p < 0.05, **p < 0.01, ***p < 0.001 compared with vehicle-treated WT mice; #p < 0.05, ##p < 0.01, ###p < 0.001 compared with vehicle-treated AS mice, two-way ANOVA with Newman–Keuls post hoc test). VEH, Vehicle; RAPA, rapamycin.