Survival of S. Typhimurium-infected WT, TLR2−/−, TLR4−/−, and TLR9−/− mice. Age-matched WT, TLR2−/−, TLR4−/−, and TLR9−/− mice were i.g. infected with 5 × 105 CFU of S. Typhimurium, and survival was monitored every day; n ≥ 6 mice in each group. *, P < 0.05 by the log-rank curve comparison test.