FIG 2.
Systemic immune responses in mice following S. Typhimurium infection. Age-matched WT (n = 6), TLR2−/−, and TLR9−/− (n ≥ 4) mice were i.g. infected with 5 × 104 CFU of S. Typhimurium (ST), and serum was harvested at 7 days postinfection. Inflammatory cytokine (A), chemokine (B), and immunosuppressive cytokine (C) levels were measured by CBA. n.d., not detected. Values are expressed in pg/ml or ng/ml serum as the means ± standard deviations (SD); statistical significance was determined as P values of <0.05 (*) and <0.01 (**) compared with infected WT mice.