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Multinucleated giant cells (MGCs) engulf fungal cells in the lungs of immunized mice. Lung sections obtained from three mice, at 13 days after infection with strain R265, were stained with hematoxylin-eosin (HE) or alcian blue (AB). C. gattii cells were stained with alcian blue. Each section was observed at magnifications of ×40 (A), ×200 (B), and ×1,000 (C).
