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. 2015 Mar 17;10(3):e0120814. doi: 10.1371/journal.pone.0120814

Fig 3. Relationship between disease severity and age in children with and without any eye findings.

Fig 3

Scatter plot of FOS-MSSI score versus age (in years) at last FOS-MSSI score assessment, showing regression (trend) lines* for children with and without any eye findings. Children with eye findings (solid grey dots) had more severe disease across all ages than children without any eye findings (open black circles). Disease severity increased with age in both children with and without eye findings. CV = cornea verticillata; FOS-MSSI = Fabry Outcome Survey Mainz severity score index. *Regression lines were determined by the following equations: 1. With any eye findings: FOS-MSSI (removing cornea verticillata) = 3.638976 + 0.613467 × age at FOS-MSSI assessment. 2. Without any eye findings: FOS-MSSI (removing cornea verticillata) = 1.646037 + 0.497238 × age at FOS-MSSI assessment.