Table 2.
a. Baselinea | b. 2 weeks | c. 4 weeks | d. 6 weeks | e. 8 weeks | p values* | |||||
---|---|---|---|---|---|---|---|---|---|---|
b–a | c–a | d–a | e–a | |||||||
MMT sum scores and the change in MMT sum scores | ||||||||||
Group A (n = 8) | 110.00 ± 12.56 | 118.13 ± 11.15 | 122.75 ± 9.99 | 123.81 ± 10.16 | 124.50 ± 9.07 | 0.046 | 0.015 | 0.016 | 0.011 | |
– | 8.13 ± 9.49 | 12.75 ± 11.29 | 13.81 ± 12.44 | 14.50 ± 11.87 | ||||||
Group B (n = 8) | 117.19 ± 11.50 | 123.00 ± 13.20 | 128.06 ± 13.05 | 127.81 ± 11.40 | 128.63 ± 11.21 | 0.022 | 0.019 | 0.014 | 0.006 | |
– | 5.81 ± 5.62 | 10.88 ± 10.12 | 10.63 ± 9.24 | 11.44 ± 8.36 | ||||||
Group C (n = 7) | 112.86 ± 23.83 | 120.36 ± 12.49 | 123.50 ± 10.22 | 124.36 ± 9.99 | 128.07 ± 8.01 | 0.214 | 0.151 | 0.125 | 0.059 | |
– | 7.50 ± 14.26 | 10.64 ± 17.12 | 11.50 ± 17.09 | 15.21 ± 17.29 | ||||||
All patients (n = 23) | 113.37 ± 16.02 | 120.50 ± 11.91 | 124.83 ± 10.97 | 125.37 ± 10.23 | 127.02 ± 9.34 | 0.002 | <0.001 | <0.001 | <0.001 | |
– | 7.13 ± 9.76b | 11.46 ± 12.41 | 12.00 ± 12.57 | 13.65 ± 12.30 |
MMT manual muscle testing
* Paired t test for change from baseline
aBaseline scores were those immediately before intravenous immunoglobulin administration
bPrimary endpoint