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. 2015 Jan 11;262(3):752–759. doi: 10.1007/s00415-014-7618-y

Table 2.

Sequential changes in MMT sum scores after intravenous immunoglobulin administration

a. Baselinea b. 2 weeks c. 4 weeks d. 6 weeks e. 8 weeks p values*
b–a c–a d–a e–a
MMT sum scores and the change in MMT sum scores
 Group A (n = 8) 110.00 ± 12.56 118.13 ± 11.15 122.75 ± 9.99 123.81 ± 10.16 124.50 ± 9.07 0.046 0.015 0.016 0.011
8.13 ± 9.49 12.75 ± 11.29 13.81 ± 12.44 14.50 ± 11.87
 Group B (n = 8) 117.19 ± 11.50 123.00 ± 13.20 128.06 ± 13.05 127.81 ± 11.40 128.63 ± 11.21 0.022 0.019 0.014 0.006
5.81 ± 5.62 10.88 ± 10.12 10.63 ± 9.24 11.44 ± 8.36
 Group C (n = 7) 112.86 ± 23.83 120.36 ± 12.49 123.50 ± 10.22 124.36 ± 9.99 128.07 ± 8.01 0.214 0.151 0.125 0.059
7.50 ± 14.26 10.64 ± 17.12 11.50 ± 17.09 15.21 ± 17.29
 All patients (n = 23) 113.37 ± 16.02 120.50 ± 11.91 124.83 ± 10.97 125.37 ± 10.23 127.02 ± 9.34 0.002 <0.001 <0.001 <0.001
7.13 ± 9.76b 11.46 ± 12.41 12.00 ± 12.57 13.65 ± 12.30

MMT manual muscle testing

* Paired t test for change from baseline

aBaseline scores were those immediately before intravenous immunoglobulin administration

bPrimary endpoint