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. Author manuscript; available in PMC: 2015 Mar 18.
Published in final edited form as: Immunobiology. 2011 Jul 13;217(2):169–175. doi: 10.1016/j.imbio.2011.06.003

Figure 1. Representation of the four main isoforms of CD46.

Figure 1

These isoforms arise from the alternative splicing of exon B, giving rise to a BC or C isoform. The exon coding for Cyt1 can also be spliced to produce either Cyt1 or Cyt2 tail. As Cyt1 contains a stop codon, Cyt1 and Cyt2 sequences are different. Hence, the four main isoforms are BC1, C1, BC2 and C2.