Table 2.
MFWS grades at each study time point.
| Day | NLF | Number (%)a of subjects with MFWS grade | ||||||
|---|---|---|---|---|---|---|---|---|
| 0 | 0.5 | 1 | 1.5 | 2 | 2.5 | 3 | ||
| Day 0 (N = 48) |
Right | — | — | — | — | 30 (62.5) | 16 (33.3) | 2 (4.2) |
| Left | — | — | — | — | 26 (54.2) | 19 (39.6) | 3 (6.3) | |
|
| ||||||||
| Day 14 (N = 48) |
Right | 4 (8.3) | 18 (37.5) | 19 (39.6) | 7 (14.6) | — | — | — |
| Left | 6 (12.5) | 11 (22.9) | 24 (50.0) | 7 (14.6) | — | — | — | |
|
| ||||||||
| Day 30 (N = 47)b |
Right | 4 (8.5) | 18 (38.3) | 22 (46.8) | 3 (6.4) | — | — | — |
| Left | 5 (10.6) | 16 (34.0) | 24 (51.1) | 2 (4.3) | — | — | — | |
|
| ||||||||
| Day 90 (N = 47)b |
Right | 4 (8.5) | 15 (31.9) | 25 (53.2) | 3 (6.4) | — | — | — |
| Left | 4 (8.5) | 13 (27.7) | 27 (57.4) | 3 (6.4) | — | — | — | |
|
| ||||||||
| Day 180 (N = 47)b |
Right | 1 (2.1) | 14 (29.8) | 25 (53.2) | 6 (12.8) | 1 (2.1) | — | — |
| Left | 1 (2.1) | 13 (27.7) | 26 (55.3) | 5 (10.6) | 2 (4.3) | — | — | |
|
| ||||||||
| Day 270 (N = 47)b |
Right | — | 14 (29.8) | 20 (42.6) | 12 (25.5) | — | — | 1 (2.1) |
| Left | — | 13 (27.7) | 23 (48.9) | 10 (21.3) | — | 1 (2.1) | — | |
Grade 0 = no wrinkle; Grade 0.5 = very shallow yet visible wrinkle; Grade 1 = fine wrinkle; Grade 1.5 = visible wrinkle and clear indentation; Grade 2 = moderate wrinkle; Grade 2.5 = prominent and visible wrinkle; Grade 3 = deep wrinkle
aPercentages are based on the number of subjects with available data.
bOne subject was lost to follow-up after Day 14.
Safety analysis data set: SAF.
MFWS = Modified Fitzpatrick Wrinkle Scale, N = number of subjects with available data, and NLF = nasolabial fold.