Fig 3. Computed μ_eff spectra and spherical geometry thickness recovery data.

(a) Five computed μ_eff spectra for different chromophore concentrations that span the range in breast tissue from the literature (each slab’s chromophore concentrations are listed below). The μ_eff variability is minimal around 925 nm. (b) Thickness recovered for the 4 cm chord distance in a spherical medium with the same chromophore concentrations as in Slab 1. The reference transmittance, T ₀(λ*), for the application of Eq. (8) is taken to be the one for a 5 cm thick infinite slab with the chromophore concentrations of Slabs 1–5, as indicated in the x axis. Chromophore concentrations of each slab are listed as ([HbO], [Hb], [water], [lipid]): Slab 1 (14uM, 7uM, 20%, 65%); Slab 2 (17uM, 11uM, 30%, 45%); Slab 3 (18uM, 10uM, 30%, 60%); Slab 4 (28uM, 12uM, 45%, 30%); Slab 5 (6uM, 4uM, 20%, 75%).