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. 2015 Mar 17;10(3):e0119886. doi: 10.1371/journal.pone.0119886

Table 2. Summary of reversion within CTL epitopes following transmission in the presence or absence of the selecting HLA type.

PID Days PI Optimal epitope a Restricting HLA HLA-association b
AS2–0016 EWDRLHPVHAGPIAPGQMR B*42 +
14 ....T..............
463 ...................
MQMLKDTINEEAAEWDRLHP B*57
14 .................T..
463 ....................
AS2–0341 MVHQAISPRTLNAWVKVIE B*57/B*58 +
14 ....P..............
342 ...................
LQGQMVHQAISPRTLNAWVK B*1510
14 ........P...........
342 ....................
SQNYPIVQNLQGQMVHQAI C*16
14 .................P.
342 ...................
AS2–1037 GTEELRSLYNTVATLYCVHEK A*3002
34 ........F..T.......AR
321 .....................
EELRSLYNTVATLYCVHEK A*29
34 ......F..T.......AR
321 ...................
TEELRSLYNTVATLYCVHE A*02
34 .......F..T.......A
321 ...................

aBold residues denotes known CTL escape mutation

b(+): presence of HLA-association, (−): absence of previously identified HLA association

Underlining denotes the CTL epitope in the peptide sequence