Table 3. Summary of reversion of HLA associated mutations following transmission in the presence or absence of the selecting HLA type.

PID	Gag codon position	Mutation	Restricting HLA a	HLA-association b
AS1–0703	91	R-K	C*06	+
AS2–0341	230	D-E	None	−
AS2–0483	242	N-T	B*57/B*58:01/C*08:02	−
AS2–0945	332	N-T	B*39:10	−
AS2–1037	79	F-Y	A*36:01/A*01/C*14/A*02:02/A*29	−
	82	I-V	None	−
	90	A-E	None	−
	91	R-K	A*74/A*66/C*06	−
	312	E-D	B*44/A*36:01/C*04	−
AS21–0187	228	L-M	B*49:01	−
AS3–0268	79	F-Y	A*36:01/A*01/C*14/A*02:02/A*29	+
AS3–0458	69	R-Q	None	−
AS3–0513	15	R-K	C*18:01	−
	228	I-M	None	−
AS3–0942	15	T-K	A*68:01/A*66:01/B*42:02	−
	79	F-Y	A*36:01/A*01/C*14/A*02:02/A*29	−
	106	K-E	None	−
	110	E-K	None	−
	173	S-T	A*29:02/A*26/B*81	+
	182	G-Q	B*81	−
	223	V-I	C*12/C*12:03	−
	248	T-A	None	−
	312	E-D	B*44/A*36:01	−
	315	G-N	B*53:01/B*57:03/C*17:01/B*44:03/C*04:01/B*42	−
	384	R-K	B*58:02	−
	478	S-P	B*57	−
	481	K-R	A*30:01	−
AS5–0968	30	Q-R	C*06	+

a"None" indicates no known HLA-association of mutation

b(+): presence of HLA-association, (−): absence of previously identified HLA association

Bold restricting HLA indicates the HLA which is positively associted with the non-adapted mutation at one-year post infection