Figure 4.

Changes in functional connectivity (FC) with the hippocampus (HIPP) after acupunture minus before acupuncture (ACU) in relation to delta temperature correlation scores after ACU minus before ACU. Increased hypothalamus-hippocampus functional connectivity (HYP–HIPP FC) after acupuncture (after ACU) was positively correlated with ACU-induced change in core body temperature suggesting that increased dopamine modulation during ACU was possibly associated with increased poststimulation limbic system and spinothalamic tract connectivity (r = 0.66; P = 0.03).