Figure 6.

Changes in functional connectivity (FC) with the insula after acupuncture minus before acupuncture (ACU) in relation to delta glucose (GLU) correlation scores after ACU minus before ACU. Increased hypothalamus-insula functional connectivity (HYP-INS FC) after acupuncture (after ACU) was positively correlated with ACU-induced change in GLU suggesting that increased dopamine modulation during ACU was deemed to be associated with increased poststimulation limbic system and spinothalamic tract connectivity (r = 0.66; P = 0.03).