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. 2015 Mar 17;10(3):e0119832. doi: 10.1371/journal.pone.0119832

Fig 5. Reduced migratory and invasive capabilities of cancer cells following AUY922 treatment.

Fig 5

Cells were seeded onto either collagen or matrigel-coated polycarbonate filters to determine their migratory and invasive potentials, respectively. Cells were incubated in modified Boyden chambers with or without the indicated doses of AUY922 for 24 hours, and the cells that penetrated the filter were stained and counted using a light microscope. Bars represent the mean ± SD of three wells. *p< 0.01 and **p< 0.001 in comparison with HCC827 cells.