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. 2015 Mar 17;10(3):e0120164. doi: 10.1371/journal.pone.0120164

Fig 1. Femoral BMD and serum markers of bone turnover in mice infused for 12 days.

Fig 1

A. BMD was measured in vivo at beginning and end of infusion with vehicle (VEH) or PTH (40 μg/kg/d) in WT and Cox2 KO mice and the percent change calculated relative to the beginning BMD for each mouse. B, C. Serum parameters for bone formation (P1NP) and bone resorption (CTX) were measured at the time of euthanasia. Bars are means ± SEM for 7 WT and 7 KO mice treated with vehicle and 8 WT and 8 KO treated with PTH. aSignificant effect of PTH, p<0.01. bSignificant effect of genotype, p<0.01.