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. 2015 Mar 17;10(3):e0120164. doi: 10.1371/journal.pone.0120164

Table 4. Cortical morphometry by μCT in the midshaft femoral region of WT and Cox2 KO mice after infusion with vehicle or PTH for 12 days.

Parameter WT mice Cox2 KO mice
Vehicle (7) PTH (8) Vehicle (7) PTH (8)
Cortical area (mm2) 1.02 ± 0.03 0.97 ± 0.03 0.98 ± 0.02 1.23 ± 0.07 a , b
Cortical thickness (mm) 0.21 ± 0.01 0.19 ± 0.01 0.20 ± 0.01 0.25 ± 0.01 a , b
Cortical porosity (%) 0.55 ± 0.09 0.56 ± 0.07 0.57 ± 0.07 0.39 ± 0.03
Subperiosteal area (mm2) 2.17 ± 0.03 2.08 ± 0.06 2.23 ± 0.04 2.43 ± 0.14
Subendosteal area (mm2) 1.15 ± 0.02 1.11 ± 0.04 1.25 ± 0.04 1.20 ± 0.09

Data are means ± SEM for (n) mice.

aSignificant effect of PTH, p<0.01.

bSignificant effect of genotype, p<0.05.