Table 5. Body weight and serum calcium (Ca) in 3-mo old wild type (WT) and Cox2 KO mice infused with vehicle or PTH for 21 days.
Parameter | WT mice | Cox2 KO mice | ||
---|---|---|---|---|
Vehicle (6) | PTH (7) | Vehicle (6) | PTH (7) | |
Start weight (g) | 26.2 ± 0.31 | 26.1 ± 0.49 | 23.7 ± 0.23 b | 24.1 ± 0.38 b |
End weight (g) | 28.9 ± 0.32 | 28.6 ± 0.48 | 26.4 ± 0.28 b | 27.2 ± 0.27 c |
Ca (mg/dl) at end | 9.34 ± 0.18 | 11.3 ± 0.17 a | 9.24 ± 0.13 | 11.4 ± 0.13 a |
Data are means ± SEM for (n) mice.
aSignificant effect of PTH, p<0.01.
bSignificant effect of genotype, p<0.01,
cp<0.05.