Figure 4.
Evaluation of the pretreatment with naloxone (2 mg/kg, i.p.) in the effect of C. cordiifolius essential oil (CcEO; 50 and 100 mg/kg, i.p.) and morphine (7.5 mg/kg, i.p.) in the acetic acid induced writhing test. Results are expressed as mean ± SEM (n = 8) with significance level set at P < 0.05. *When compared to the vehicle group; awhen compared to morphine group.