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. 2015 Mar 3;2015:806418. doi: 10.1155/2015/806418

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Copyright © 2015 M. J. Laye et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Protein levels as measured by western blot of traditional training markers in runners (solid bars) or pair sedentary controls (open bars) in resting vastus lateralis biopsies. Glutathione peroxidase 1 (a) and manganese superoxide dismutase (MnSOD) (b) were significantly higher in runners (n = 10, P < 0.001, 2-way ANOVA). Mitochondrial complex IV (COXIV) (c) was significantly higher in runners (n = 10, P < 0.001, 2-way ANOVA). Post hoc significance as determined by Bonferroni corrected t-test is indicated by a ^*(P < 0.05). Myosin heavy chain IIa (d), vascular endothelial growth factor (VEGF) (e), heat shock protein 70 (HSP70) (f), nor glucose transporter 4 (GLUT4) (g) did not differ between groups. Proteins of interest are normalized to β-tubulin as a loading control that did not differ between groups. Representative blots are shown in (h), with C indicating control and R indicating runner.