Table 1.
General and clinical characteristics of the paediatric patients with acute myeloid leukaemia.
| Characteristic | Patients | P | |
|---|---|---|---|
| Group A with EIa | Group B without EI | ||
| (n = 20) | (n = 20) | ||
| Age (years) | 0.718 | ||
| Median (min–max) | 9 (2–15) | 9.5 (2–15) | |
| Sex | 0.525 | ||
| Male | 11 (55%) | 11 (55%) | |
| Female | 9 (45%) | 9 (45%) | |
| Leukocyte count (103/μL) | 0.698 | ||
| Median | 28 250 | 26 900 | |
| Minimum–maximum | 9 700–125 000 | 5 800–154 700 | |
| Morphological subtype (FABb) | 0.941 | ||
| M0, M1, M2 | 6 (30%) | 4 (20%) | |
| M3 | 1 (5%) | 1 (5%) | |
| M4, M5 | 11 (55%) | 12 (60%) | |
| M6 | 1 (5%) | 1 (5%) | |
| M7 | 1 (5%) | 2 (10%) | |
| Karyotype | 0.900 | ||
| Normal | 8 (40%) | 6 (30%) | |
| t(8:21)aml/atg8 | 2 (10%) | 3 (15%) | |
| t(15:4)q+ | 0 (0%) | 1 (5%) | |
| t(9:22)abr/bcl | 1 (5%) | 1 (5%) | |
| t(9:11)p22,q23 | 1 (5%) | 1 (5%) | |
| No data | 8 (40%) | 8 (40%) | |
| Risk (by karyotype) | 0.870 | ||
| Normal | 4 (17%) | 3 (13%) | |
| Intermediate | 8 (33%) | 6 (25%) | |
| High | 2 (8%) | 1 (4%) | |
| Risk (BFMc) | 0.669 | ||
| Low | 3 (15%) | 3 (15%) | |
| High | 17 (85%) | 17 (85%) | |
aEI: early intensification.
bFAB: French-American-British classification.
cBFM: Berlin-Frankfurt-Münster study [39].