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. 2015 Mar 17;10(3):e0120531. doi: 10.1371/journal.pone.0120531

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© 2015 Mühlenberg et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 4 — A. Cytotoxicity assays (3days) combining 2DG with IM and ABT-263. B. Western Blot studies after 24h of co-treatment of 2DG with either IM or ABT-263. C. Induction of apoptosis (caspase 3/7 activation) after 16h of treatment with combinations of 2DG and ABT-263. D. Expression of proapoptotic (BIM) and antiapoptotic (BCL-2, BCL-XL, MCL-1) BCL-2 proteins after single and combined treatment (16h) with 2DG and the BCL-2 antagonist ABT-263.E. Time course studies of 2DG with IM co-treatment (left panel) and 4h IM pre-treatment before addition of 2DG (right panel).