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. 2014 Jul 18;14:71. doi: 10.1186/s12935-014-0071-2

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Copyright © 2014 Wang et al.; licensee Springer

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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EC9706 cell xenograft tumor for detecting myricetin sensitizing tumors to 5-FU treatment in vivo. EC9706 cells were implanted subcutaneously in immunodeficient female BALB/C nude mice. Mice treated with myricetin alone, 5-FU alone, and myricetin + 5-FU combination. A. The xenograft tumors from nude mice in each groups after 2 months implantation. B. Shown are medium tumor weights of each group as function of time after implantation. The data curve showed that 5-FU combination with myricetin could inhibit the tumor growth significantly, compared with other three groups.