Table 2.
The cellular profile of sputum, asthma phenotypes, and ACQ score at visit 1. Values are presented as mean ± SD.
| SN group | MMA group | RA group | |
|---|---|---|---|
| Sputum cytology | |||
| Total cells (×106/mL) | 5.41 ± 7.47 | 4.96 ± 4.13 | 5.04 ± 4.0 |
| Viability (%) | 81.10 ± 10.67 | 80.6 ± 11.31 | 80.9 ± 12.6 |
| Squamous cells (%) | 5.89 ± 5.74 | 6.85 ± 10.8 | 9.31 ± 7.97 |
| Epithelial cells (%) | 0.85 ± 0.52 | 1.1 ± 0.7 | 0.62 ± 0.49 |
| Macrophages (%) | 59.03 ± 18.57 | 56.2 ± 21.6 | 59.25 ± 15.4 |
| Lymphocytes (%) | 4.99 ± 6.44 | 4.79 ± 6.34 | 6.56 ± 3.25 |
| Neutrophils (%) | 27.12 ± 18.8 | 24.15 ± 20.1 | 21.94 ± 15.31 |
| Eosinophils (%) | 3.05 ± 3.89 | 7.9 ± 14.57 | 2.75 ± 3.61 |
| Inflammatory phenotype, n (%) | |||
| Eosinophilic | 8 (47%) | 18 (55%) | 7 (44%) |
| Neutrophilic | 1 (6%) | 0 | 0 |
| Paucigranulocytic | 8 (47%) | 14 (42%) | 9 (56%) |
| Mixed granulocytic | 0 | 1 (3%) | 0 |
| ACQ score | 0.96 ± 0.58 | 1.31 ± 1.06 | 2.4 ± 0.81*** |
SN, steroid-naïve asthma; MMA, mild to moderate asthma; RA, refractory asthma. *** P < 0.001 versus MMA group and SN group.