Table 1.
Patients’ characteristics at enrolment according to cancer-categories
| Variables | Categories | Total | ADC | NADC | Without cancer | P value |
|---|---|---|---|---|---|---|
| Total | 16268 | 688 | 471 | 15109 | ||
| Gender | Male | 12116 (74.5) | 549 (79.8) | 360 (76.4) | 11207 (74.2) | 0.003 |
| Female | 4152 (25.5) | 139 (20.2) | 111 (23.6) | 3902 (25.8) | ||
| Age at enrolment (years) | 18-34 | 9797 (60.2) | 369 (53.6) | 228 (48.4) | 9200 (20.9) | <0.001 |
| 35-44 | 4278 (26.3) | 189 (27.5) | 121 (25.7) | 3968 (26.3) | ||
| 45-54 | 1538 (9.5) | 91 (13.2) | 71 (15.1) | 1376 (9.1) | ||
| 55-64 | 513 (3.1) | 36 (5.2) | 41 (8.7) | 436 (2.9) | ||
| >65 | 142 (0.9) | 3 (0.4) | 10 (2.1) | 129 (1.0) | ||
| Mean (SD) | 34.2 (9.8) | 35.6 (10.3) | 37.8 (11.9) | 34.1 (9.7) | <0.001 | |
| Year of enrolment | 1986-1989 | 2275 (14.0) | 79 (16.8) | 135 (19.6) | 2061 (13.6) | <0.001 |
| 1990-1993 | 2835 (17.4) | 99 (21.0) | 121 (17.6) | 2615 (17.3) | ||
| 1994-1997 | 2465 (15.1) | 98 (20.8) | 137 (19.9) | 2230 (14.8) | ||
| 1998-2001 | 2522 (15.5) | 73 (15.5) | 101 (14.7) | 2348 (15.5) | ||
| 2002-2005 | 2539 (15.6) | 70 (14.9) | 108 (15.7) | 2361 (15.6) | ||
| 2006-2012 | 3632 (22.3) | 52 (11.0) | 86 (12.5) | 3494 (23.1) | ||
| IDUs | No | 8374 (51.5) | 363 (52.8) | 200 (42.5) | 7811 (51.7) | <0.001 |
| Yes | 7894 (48.5) | 325 (47.2) | 271 (57.5) | 7298 (48.3) | ||
| HBV/HCV co-infection | No | 8374 (51.5) | 363 (52.8) | 200 (42.5) | 7811 (51.7) | <0.001 |
| Yes | 7894 (48.5) | 325 (47.2) | 271 (57.5) | 7298 (48.3) | ||
| CD4 cell count , cell/mm3 | 0-49 | 1151 (7.1) | 95 (13.8) | 28 (5.9) | 1028 (6.8) | <0.001 |
| 50-99 | 940 (5.8) | 59 (8.6) | 31 (6.6) | 850 (5.6) | ||
| 100-199 | 2038 (12.5) | 136 (19.8) | 70 (14.9) | 1832 (12.1) | ||
| 200-349 | 3464 (21.3) | 144 (20.9) | 100 (21.2) | 3220 (21.3) | ||
| 350-499 | 3346 (20.6) | 110 (16.0) | 107 (22.7) | 3129 (20.7) | ||
| ≥500 | 5329 (32.8) | 144 (20.9) | 135 (28.7) | 5050 (33.4) | ||
| Mean (SD) | 416.8 (298.6) | 316.7 (272.6) | 401.8 (300.8) | 421.8 (298.9) | <0.001 | |
| Log10 HIVRNA, copies/mL | Mean (SD) | 3.1 (1.4) | 3.3 (1.5) | 3.0 (1.4) | 3.1 (1.4) | NS |
| Treatment-naïve | No | 14179 (87.2) | 610 (88.7) | 412 (87.5) | 13157 (87.1) | NS |
| Yes | 2089 (12.8) | 78 (11.3) | 59 (12.5) | 1952 (12.9) |
Patients with both ADC and NADC diagnosis (n = 36) were considered as ADC or NADC on the basis of which first occurred cancer.
Abbreviations: ADC AIDS-defining-cancer, NADC non-AIDS-defining-cancer, SD standard deviation, NS not statistically significant (p > 0.05), IDUs intravenous drug users, HBV/HCV co-infection hepatitis B virus/hepatitis C virus positivity.