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Release profile of DOX from DOX/HDPEPM or free DOX incubated at pH 5.0, pH 6.8, or pH 7.4 (n=3).
Abbreviations: DOX, doxorubicin; HDPEPM, nanoconjugate formed by covalent attachment of fragment HAb18 F(ab′)2 and 2,3-dimethylmaleic anhydride to polyethylenimine-modified poly(β-L-malic acid).
