Table 2.
Patient | Age, y | DD, y | Preoperative levodopa, mg | UPDRS-III score | Neurons, n | Emotion-related neurons, n |
1 | 64 | 14 | 1,375 | 31 | 8 | 1 |
2 | 61 | 14 | 1,200 | 37 | 5 | 0 |
3 | 46 | 15 | 1,000 | 40 | 10 | 1 |
4 | 63 | 30 | 1,250 | 50 | 2 | 1 |
5 | 53 | 12 | 700 | 37 | 7 | 1 |
6 | 69 | 9 | 750 | 47 | 2 | 0 |
7 | 49 | 12 | 1,550 | 65 | 4 | 1 |
8 | 53 | 11 | 1,663 | 45 | 5 | 1 |
9 | 64 | 17 | 1,500 | 31 | 11 | 2 |
10 | 42 | 9 | 740 | 33 | 16 | 3 |
11 | 55 | 19 | 1,980 | 35 | 8 | 2 |
12 | 60 | 14 | 1,060 | 18 | 7 | 0 |
13 | 43 | 9 | 1,100 | 34 | 5 | 2 |
Age refers to age on the day of surgery; DD, PD duration; preoperative levodopa, dose/day in mg, including levodopa-equivalent dosage of dopamine agonist (patient 4 was also treated with mianserin, and patients 6, 7, 12, and 13 were also treated with citalopram); UPDRS-III, motor score of the Unified Parkinson´s Disease Rating Scale in the off-medication condition; neurons, number of subthalamic neurons unrelated to eye movements; emotion-related neurons, number of neurons responding to emotional stimuli.