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Novel miRNAs display a tissue-specific pattern of expression. Shown are the Jaccard index value for the overlap of expressed miRNAs between any two tissues for the novel miRNAs (A) and the miRBase miRNAs (B). A miRNA was considered to be expressed in each tissue if the miRNA had a normalized expression of ≥1/100 the expression of endogenous SNORD44. (C) Principal-component analysis of the sequence data can cluster the samples based upon tissue types.
