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. 2015 Mar 18;9:89. doi: 10.3389/fncel.2015.00089

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Copyright © 2015 Williams and Hablitz.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Emergence of slow afterdepolarizations (sADPs) in b-AC MCs in presence of 4-AP. (A) Representative response of a L2/3 b-AC MC to a 475 pA depolarizing current pulse before (black) and after (red) bath application of 4-AP. Following application of 4-AP, a sADP was observed following repetitive firing. (B) Summary plot showing that a significant s-ADP was observed in all b-AC MCs in presence of 4-AP (n = 10). *p < 0.05.