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. 2015 Mar 17;10(3):e0120161. doi: 10.1371/journal.pone.0120161

Table 1. Grouping of adverse events of second—line anti-tuberculosis drugs.

CATEGORY ADVERSE EVENTS
OTOTOXICITY Tinnitus, Hearing loss, Deafness, Disequilibrium, Vertigo
PSYCHIATRIC Irritability, Anxiety, Depression, Suicidal Ideation, Personality Changes, Depression, Psychosis,
NEUROLOGICAL Dizziness, Insomnia, Vertigo, Convulsion, Syncope, Peripheral neuropathy, Blurring of Vision, Parasthesia, Fasciculation, Numbness, Incoherent speech, Oculogyric syndrome, Seizures, Palpitation, Atrophy at injection site
ENDOCRINE Poor glycemic control, Hypothyroidism
DERMATOLOGICAL Skin pigmentation, Photosensitivity, Dry skin, Stevens-Johnson syndrome, Fungal Infection, Itching, Skin reaction, Urticaria
GASTROINTESTINAL Nausea, Vomiting, Gastritis, Ulcers, Hepatitis, Bowel obstruction, Abdominal discomfort, Gastrointestinal bleeding, Abdominal pain, Abdominal upset, Anorexia, Diarrhea, Dyspepsia, Hepatotoxicity
ELECTROLYTE ABNORMALTIES Dehydration, Hypocalcaemia, Hypomagnesaemia, Hypokalaemia
NEPHROLOGICAL Renal Insufficiency
ALLERGIC Allergic reactions
ARTHRALGIA Joint pain, Ankle swelling and pains, Arthritis, Myalgia, Stiffness of fingers
GENERAL BODY PAIN Pain in the lower back, headache, pain at injection site, Generalized body pain, musculoskeletal pain, Pain radiating to the back.
OTHERS Weight loss, Vaginal discharges, Anemia, Body weakness, Palpitation, Fever, Hair loss, Bitterness of mouth, Heart failure, Hypertension, No menstruation, Pains in the legs, Restlessness, Tendinitis, Unstable temperature.